Multicomponent synthesis of 4-unsubstituted 5-nitropyridine derivatives Научная публикация
| Журнал |
Synthetic Communications
ISSN: 0039-7911 , E-ISSN: 1532-2432 |
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| Вых. Данные | Год: 2020, Том: 50, Номер: 16, Страницы: 2432-2439 Страниц : 8 DOI: 10.1080/00397911.2020.1780261 | ||||
| Ключевые слова | Green chemistry, 5-nitro-1,4-dihydropyridines, 5-nitropyridines, multicomponent reaction | ||||
| Авторы |
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| Организации |
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Информация о финансировании (1)
| 1 | Российский фонд фундаментальных исследований | 19-03-00376 |
Реферат:
Multicomponent reaction of 2-nitroacetophenone, urotropine (or paraformaldehyde), β-dicarbonyl compound and ammonium acetate afforded five new 4-unsubstituted 5-nitro-6-phenyl-1,4-dihydropyridine derivatives, oxidation of which provided the corresponding 5-nitro-6-phenylpyridines. The proposed approach for the synthesis of 4-unsubstituted 5-nitro-6-phenyl-1,4-dihydropyridines and their subsequent aromatization into pyridines made it possible to reduce the total reaction time by more than 200 times and the overall yield of 5-nitro-6-phenylpyridine by 2 times compared with the known methods.
Библиографическая ссылка:
Kulakov I.V.
, Oleshchuk A.L.
, Koveza V.A.
, Palamarchuk I.V.
Multicomponent synthesis of 4-unsubstituted 5-nitropyridine derivatives
Synthetic Communications. 2020. V.50. N16. P.2432-2439. DOI: 10.1080/00397911.2020.1780261 WOS Scopus РИНЦ OpenAlex
Multicomponent synthesis of 4-unsubstituted 5-nitropyridine derivatives
Synthetic Communications. 2020. V.50. N16. P.2432-2439. DOI: 10.1080/00397911.2020.1780261 WOS Scopus РИНЦ OpenAlex
Даты:
| Поступила в редакцию: | 22 дек. 2019 г. |
| Опубликована online: | 23 июн. 2020 г. |
| Опубликована в печати: | 17 авг. 2020 г. |
Идентификаторы БД:
| Web of science: | WOS:000547312400001 |
| Scopus: | 2-s2.0-85087375165 |
| РИНЦ: | 45496904 |
| OpenAlex: | W3036963612 |